Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Dong quai (Angelica sinensis) has a long history of use in traditional Chinese medicine (TCM), primarily as a "female tonic" for gynecological conditions, but it is also sometimes used in formulas intended to support joint health and alleviate symptoms of conditions like rheumatoid arthritis (RA). In TCM, dong quai is believed to "invigorate blood" and "dispel wind," concepts associated with alleviating pain and inflammation, which are symptoms present in RA. Traditional formulas for arthritis often combine dong quai with other herbs to enhance its purported anti-inflammatory and analgesic effects.

Scientific studies on dong quai’s effectiveness specifically for rheumatoid arthritis in humans are very limited. Some in vitro and animal studies have suggested that dong quai and its active compounds (such as ferulic acid) may possess anti-inflammatory and immunomodulatory properties. For example, animal models have shown reduced markers of inflammation after dong quai administration. However, there is a lack of well-designed clinical trials in humans with RA, and most available evidence comes from traditional use or studies on mixed herbal formulas rather than dong quai alone. Thus, while dong quai is traditionally used as part of herbal protocols for joint pain and rheumatoid arthritis, scientific validation for its efficacy in this context remains insufficient.

In summary, dong quai’s use for RA is primarily rooted in tradition, with limited preclinical support but no strong clinical evidence. People considering dong quai for RA should consult a healthcare provider, especially due to potential herb-drug interactions and contraindications.

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