Evidence supporting the use of: Flavanol (mixture)
For the health condition: Rheumatoid Arthritis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavanols are a class of polyphenolic compounds found in various foods such as cocoa, tea, apples, and berries. Their anti-inflammatory and antioxidant properties have been investigated in the context of rheumatoid arthritis (RA), a chronic autoimmune disease characterized by inflammation and joint destruction. Several preclinical studies have shown that flavanols, particularly epicatechin and catechin, can modulate inflammatory pathways by inhibiting cytokines like TNF-α and IL-1β, as well as reducing oxidative stress in animal models of RA. A small number of human clinical trials have explored the effects of flavanol-rich foods (such as cocoa or green tea) on inflammatory markers in patients with RA, with some reporting modest improvements in inflammation or symptom relief. However, the evidence is limited by small sample sizes, short study durations, and heterogeneity in flavanol sources and dosages. Systematic reviews generally conclude that while there is a plausible biological mechanism and some supportive preclinical data, robust clinical evidence demonstrating clear benefits for RA patients is lacking. Thus, while flavanols are scientifically investigated for RA, the overall level of evidence supporting their clinical use remains low at this time.

More about Flavanol (mixture)
More about Rheumatoid Arthritis

Products containing Flavanol (mixture)

We currently have no products on Vitabase that contain this ingredient.