Evidence supporting the use of: Guggullipid resin
For the health condition: Rheumatoid Arthritis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Guggullipid resin, derived from the gum of the Commiphora mukul tree, has been used in traditional Ayurvedic medicine for centuries, including in the management of inflammatory conditions like rheumatoid arthritis (RA). In Ayurveda, "guggul" is considered to possess anti-inflammatory and analgesic properties, and classical texts recommend it for joint pain and swelling. However, scientific validation for its use in RA is limited. Some small clinical trials and animal studies suggest that guggul extracts may have anti-inflammatory and immunomodulatory effects, potentially by inhibiting pro-inflammatory cytokines or modulating immune cell activity. Nevertheless, these studies are generally low in quality, with small sample sizes or methodological limitations, and there is a lack of large, high-quality randomized controlled trials confirming a significant benefit in RA patients. The evidence supporting its use is therefore primarily traditional, with only weak scientific support. Safety concerns, such as potential interactions with medications and adverse effects, also need to be considered. Overall, while guggullipid resin is commonly used in traditional medicine for RA, current scientific evidence is insufficient to firmly recommend its use for this condition.
More about Guggullipid resin
More about Rheumatoid Arthritis
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gamma linolenic acid (GLA)
gamma tocopherol
genistein
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green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
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smilax
fumaria parviflora
lingusticum wallichii
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gentiana macrophylla
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15,16-Dihydrotanshinone I
Aralia
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Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
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Acetylsalicylic acid
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
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Bee venom
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Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
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Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
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Other health conditions supported by Guggullipid resin
ArthritisCholesterol (high)
Circulation (poor)
Diabetes
Hemorrhoids
Inflammation
Rheumatoid Arthritis
Triglycerides (high)
Wounds and Sores