Evidence supporting the use of: Phaeophyceae
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phaeophyceae, or brown algae (such as Ascophyllum nodosum, Laminaria, and Fucus species), have been investigated for their potential anti-inflammatory properties, which are relevant to conditions like Rheumatoid Arthritis (RA). The primary bioactive components of Phaeophyceae include fucoidans (sulfated polysaccharides), phlorotannins, and alginates, all of which have shown anti-inflammatory effects in preclinical models. A number of in vitro and animal studies indicate that extracts from brown algae can suppress pro-inflammatory cytokines, reduce oxidative stress, and modulate immune responses. For example, fucoidan has demonstrated the ability to inhibit NF-κB signaling and downregulate inflammatory mediators in cell and animal models of arthritis.

Despite these promising findings, robust clinical evidence in humans with RA is lacking. Only limited pilot or observational studies exist, and they often suffer from small sample sizes or methodological weaknesses. There is no established tradition of using Phaeophyceae specifically for RA in historical medical systems, though seaweeds have been consumed for general health in coastal cultures. Therefore, while there is scientific rationale and preclinical evidence supporting anti-inflammatory effects, there is insufficient high-quality clinical research to confirm the benefit of Phaeophyceae for RA in humans. On a scale of 0-5, the evidence rates a 2, reflecting preclinical but not clinical support.

More about Phaeophyceae
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fat liver oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Mangiferin
Myricetin
Madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
Proteoglycans
Polydatin
Polyunsaturated Fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing Phaeophyceae

We currently have no products on Vitabase that contain this ingredient.