Evidence supporting the use of: Phaeophyceae
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phaeophyceae, or brown algae (such as Ascophyllum nodosum, Laminaria, and Fucus species), have been investigated for their potential anti-inflammatory properties, which are relevant to conditions like Rheumatoid Arthritis (RA). The primary bioactive components of Phaeophyceae include fucoidans (sulfated polysaccharides), phlorotannins, and alginates, all of which have shown anti-inflammatory effects in preclinical models. A number of in vitro and animal studies indicate that extracts from brown algae can suppress pro-inflammatory cytokines, reduce oxidative stress, and modulate immune responses. For example, fucoidan has demonstrated the ability to inhibit NF-κB signaling and downregulate inflammatory mediators in cell and animal models of arthritis.

Despite these promising findings, robust clinical evidence in humans with RA is lacking. Only limited pilot or observational studies exist, and they often suffer from small sample sizes or methodological weaknesses. There is no established tradition of using Phaeophyceae specifically for RA in historical medical systems, though seaweeds have been consumed for general health in coastal cultures. Therefore, while there is scientific rationale and preclinical evidence supporting anti-inflammatory effects, there is insufficient high-quality clinical research to confirm the benefit of Phaeophyceae for RA in humans. On a scale of 0-5, the evidence rates a 2, reflecting preclinical but not clinical support.

More about Phaeophyceae
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

15,16-Dihydrotanshinone I
Abies spectabilis
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adrenal cortex
Akebia
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algal oil
alpha-linolenic acid (ALA)
alpha-lipoic acid
alpha-pinene
alpinia galangal
amber
amentoflavone
AMP-activated protein kinase (AMPK)
ampelopsin
andrographolide
anthocyanidins
anthocyanins
antler
apigenin
apocynin
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arctiin
arjunic acid
ashwagandha
astaxanthin
astragalin
baicalein
baicalin
barbasco
bee venom
Bergenia
Black Hellebore
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bogbean
borage oil
Boswellia
Boswellic Acid
bovine cartilage / glycosaminoglycan
C-phycocyanin
cannabidiol
carnosic acid
celery
Cetylated Fatty Acids
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
clematis
Clerodendrum phlomidis
cod liver oil
coenzyme Q10 (CoQ10)
cortisol
curcumin
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
Dihomo-gamma-linolenic acid
docosahexaenoic Acid
dong quai root
DPA (docosapentaenoic acid)
eicosapentaenoic acid
Eicosatetraenoic acid
EPA (eicosapentaenoic acid)
evening primrose oil
evening primrose oil
fat liver oil
fisetin
fish protein
flavanols
flavones
Flemingia philippinensis
frankincense
fructoborate
Fumaria parviflora
gamma linolenic acid (GLA)
gamma tocopherol
genistein
Gentiana macrophylla
ginger
ginkgetin
green-lipped mussel
guelder rose
Gypenoside
Harpagoside
Hellebore
horse gram
hydroxytyrosol
Hyperoside
Jatropha macrantha
Kaempferol
krill oil
luteolin
madder
mangiferin
Marine fat
Methylsulfonylmethane (MSM)
Myricetin
Myristoleate
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omega-3 fatty acids
Osthole
Palmitoylethanolamide (PEA)
Phaeophyceae
phospholipids
Piper chaba
Polydatin
polyunsaturated fat
proteoglycans
Puerarin
Qin Jiao
resveratrol
rose hips
Salicin
Salmon Oil
Salvianolic acid
saponins
Schizochytrium
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Semecarpus anacardium
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Sinomenium acutum
slippery elm bark
smilax
Stearidonic acid
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sulforaphane glucosinolate
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vitamin B6
vitamin C
vitamin D
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Products containing Phaeophyceae

We currently have no products on Vitabase that contain this ingredient.