Evidence supporting the use of: Qin Jiao
For the health condition: Rheumatoid Arthritis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Qin Jiao (Gentiana macrophylla Pall.), known in Traditional Chinese Medicine (TCM) as a herb for dispelling wind-dampness, has a long history of use in the management of musculoskeletal disorders, including conditions resembling rheumatoid arthritis (RA). In TCM, it is traditionally prescribed to "relieve pain, reduce inflammation, and benefit joints," and appears in classical formulas such as "Qin Jiao Bie Jia Tang" for chronic arthritic symptoms and joint pain. These traditional uses are grounded in centuries of empirical experience and are well documented in ancient texts and modern TCM pharmacopeias.
Scientifically, there is limited but emerging evidence to support Qin Jiao’s anti-inflammatory and immunomodulatory effects, which are relevant to RA. Some in vitro and animal studies suggest that extracts of Gentiana macrophylla may inhibit the production of pro-inflammatory cytokines and modulate immune responses. However, robust clinical trials in humans are lacking, and the available evidence is insufficient to draw strong conclusions about efficacy or safety for RA by Western medical standards.
In summary, Qin Jiao's use for RA is primarily justified by traditional practice, with some preliminary scientific findings that suggest a plausible effect but fall short of high-quality clinical validation.
Other ingredients used for Rheumatoid Arthritis
adrenal cortexAlfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fat liver oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Mangiferin
Myricetin
Madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
Proteoglycans
Polydatin
Polyunsaturated Fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides
Other health conditions supported by Qin Jiao
ArthritisBackache
Edema
Fever
Gout
Inflammation
Jaundice (adults)
Liver Detoxification
Menstrual Irregularity
Pain (general remedies for)
Rheumatoid Arthritis
Ulcers