Evidence supporting the use of: Salvianolic acid
For the health condition: Rheumatoid Arthritis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Salvianolic acid, a polyphenolic compound primarily derived from Salvia miltiorrhiza (Danshen), has been investigated for its potential therapeutic effects in Rheumatoid Arthritis (RA). Experimental studies, mostly in vitro and in animal models, suggest that salvianolic acid exhibits anti-inflammatory, antioxidative, and immunomodulatory properties. These are relevant to RA pathogenesis, where chronic inflammation and oxidative stress play key roles. For example, studies have shown that salvianolic acid B can inhibit the production of pro-inflammatory cytokines (such as TNF-α and IL-1β) and reduce oxidative damage in joint tissues. In collagen-induced arthritis models in rats, administration of salvianolic acid B reduced joint swelling and histopathological damage, likely through inhibition of NF-κB signaling and suppression of synovial hyperplasia.

However, there are currently no large-scale, high-quality clinical trials in humans directly investigating salvianolic acid for RA. Most available evidence is preclinical and the translation of these findings to effective human treatments remains uncertain. While Danshen has a history of use in traditional Chinese medicine, its application for RA specifically is not as well-documented as for cardiovascular diseases. In summary, salvianolic acid has scientific rationale and promising preclinical data for RA, but clinical evidence is lacking.

More about Salvianolic acid
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green lipped mussel
krill oil
luteolin
methylsulfonylmethane (MSM)
myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
sardines
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
watercress
white willow
alpinia galangal
smilax
fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
Antler
Apigenin
Abrus
Andrographolide
Amentoflavone
Alpha-Lipoic Acid
anthocyanidins
Ampelopsin
Actaea spicata
Arjunic Acid
Apocynin
Arctiin
Astragalin
Boswellic Acid
Baicalein
Bogbean
Boswellia
Black willow
Barbasco
bovine cartilage / glycosaminoglycan
Baicalin
Black Hellebore
Bee venom
Bergenia
Cod Liver Oil
Cortisol
Clerodendrum phlomidis
Cyanidin
Chinese Fleeceflower
Chinese Pond Turtle
Chuchuhuasi
Cetylated Fatty Acids
C-Phycocyanin
Cannabidiol
Carnosic acid
Docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
Eicosapentaenoic Acid
Evening Primrose Oil
Fat liver oil
Fructoborate
Flemingia philippinensis
Frankincense
Flavanols
Flavones
Ginkgetin
Gypenoside
Horse Gram
Hyperoside
Hellebore
Hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
Mangiferin
Myricetin
Madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
Proteoglycans
Polydatin
Polyunsaturated Fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing Salvianolic acid

We currently have no products on Vitabase that contain this ingredient.