Evidence supporting the use of: Vitamin E (tocotrienols)
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, particularly in the form of tocotrienols, has been investigated for its potential benefits in supporting or treating rheumatoid arthritis (RA) due to its antioxidant and anti-inflammatory properties. However, the majority of studies on vitamin E and RA have used tocopherols rather than tocotrienols. Some research suggests that oxidative stress contributes to the pathogenesis of RA and that antioxidants like vitamin E may help reduce disease activity by mitigating oxidative damage. Small clinical trials and animal studies have indicated that vitamin E supplementation may result in modest reductions in pain and inflammatory markers, but these effects are generally mild and not consistent across studies.

Tocotrienols, a lesser-known form of vitamin E, have demonstrated stronger antioxidant and anti-inflammatory effects in preclinical studies compared to tocopherols. However, there is a lack of robust human clinical trials specifically examining tocotrienols in the context of RA. The use of vitamin E in RA is not rooted in traditional medicine practices but is instead based on the scientific rationale of oxidative stress reduction. Major rheumatology guidelines do not currently recommend vitamin E (including tocotrienols) as a primary or adjunct therapy for RA. In summary, while there is some scientific basis for vitamin E’s use in RA, the evidence is limited, particularly for tocotrienols, and does not strongly support its routine use for this condition.

More about Vitamin E (tocotrienols)
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Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green-lipped mussel
krill oil
luteolin
Methylsulfonylmethane (MSM)
Myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
alpinia galangal
smilax
Fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
Gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
antler
apigenin
Abrus
andrographolide
amentoflavone
alpha-lipoic acid
anthocyanidins
ampelopsin
Actaea spicata
arjunic acid
apocynin
arctiin
astragalin
Boswellic Acid
baicalein
bogbean
Boswellia
Black willow
barbasco
bovine cartilage / glycosaminoglycan
baicalin
Black Hellebore
bee venom
Bergenia
cod liver oil
cortisol
Clerodendrum phlomidis
cyanidin
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
Cetylated Fatty Acids
C-phycocyanin
cannabidiol
carnosic acid
docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
eicosapentaenoic acid
evening primrose oil
fat liver oil
fructoborate
Flemingia philippinensis
frankincense
flavanols
flavones
ginkgetin
Gypenoside
horse gram
Hyperoside
Hellebore
hydroxytyrosol
Harpagoside
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mangiferin
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madder
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proteoglycans
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polyunsaturated fat
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Qin Jiao
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Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing Vitamin E (tocotrienols)

We currently have no products on Vitabase that contain this ingredient.