Evidence supporting the use of: Bromelain
For the health condition: Rhinitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Bromelain, a proteolytic enzyme extract derived from pineapples (Ananas comosus), has been investigated for its potential role in the management of rhinitis, particularly allergic rhinitis. The rationale for its use is based primarily on its anti-inflammatory, mucolytic, and immunomodulatory properties. Several in vitro and animal studies suggest that bromelain can modulate cytokine production, reduce inflammation, and decrease nasal mucus viscosity, which could theoretically alleviate nasal congestion and other rhinitis symptoms.
A small number of clinical studies have evaluated bromelain in patients with sinusitis or rhinosinusitis, conditions closely related to rhinitis. For example, a double-blind, placebo-controlled study (Gupta et al., 2001) found that bromelain supplementation led to a faster recovery and improvement of symptoms in children with acute sinusitis. However, high-quality randomized controlled trials specifically addressing bromelain for allergic or non-allergic rhinitis remain limited. Systematic reviews acknowledge some promise but emphasize the lack of robust, large-scale human data.
In summary, the use of bromelain for rhinitis is supported by a modest amount of scientific evidence, primarily from mechanistic and small clinical studies. While there is biological plausibility and some positive findings, the overall clinical evidence is insufficient to strongly recommend bromelain as a standard therapy for rhinitis. More rigorous and focused trials are needed.
Other ingredients used for Rhinitis
alpha-pinenebenegut perilla (proprietary)
bifidobacterium bifidum
bifidobacterium lactis
black currant
black pepper
bromelain
bupleurum falcatum
chamomile
fennel
lactobacillus casei
lactobacillus gasseri
lactobacillus paracasei
lactiplantibacillus plantarum
lovage
magnesium
purple butterbur root
quercetin
vitamin C
zinc
cardamom
malabar nut
inula racemosa
anise
tylophora
Anamarrhena
Asarum heterotropoides
Arisaema
Asarum sieboldii
Bryonia
Baphicacanthus cusia
Bifidobacterium animalis
Belamcanda
Chinese Mountain Ant
Cineole
Cinidium
Chaenomeles lagenaria
Ephedra
European Elder
Elder
Goldthread
Other health conditions supported by bromelain
Abdominal PainAbscesses
Allergies (respiratory)
Arthritis
Blood Clots (prevention of)
Bruises (healing)
Burns and Scalds
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Cartilage Damage
Chemotherapy (reducing side effects)
Circulation (poor)
Colitis
Cuts
Edema
Gastritis
Gingivitis
Inflammation
Injuries
Pain (general remedies for)
Protein Digestion (poor)
Rhinitis
Rhinitis, Allergic
Sinus Infection
Sprains
Surgery (healing from)
Tendonitis
Wounds and Sores
Products containing bromelain
Pure Encapsulations
A.C. Formula II
Pure Encapsulations
A.I. Enzymes
Pure Encapsulations
AI Formula
Designs For Health
AllerGzyme™
Integrative Therapeutics
Bio-Zyme
Pure Encapsulations
Bromelain 2400 500 mg
Pure Encapsulations
Bromelain 2400 500 mg
Douglas Laboratories
Bromelain 500 mg
Douglas Laboratories
Cysto Renew ®
Integrative Therapeutics
EHB
Douglas Laboratories
Glucosamine + MSM Forte ™
Douglas Laboratories
Glucosamine Plus ™
Pure Encapsulations
Hist Reset
Designs For Health
HistaEze™
Thorne
Joint Support Nutrients AR-Encap
Vitabase
Life's Essentials Plus
Designs For Health
Pancreatic Enzymes Plus
Designs For Health
Pulmonary Revive™
Vitabase
Quercetin Plus
Douglas Laboratories
Quercetin-Bromelain Complex
Thorne
Quercetin Complex Quercenase
Metagenics
Sinuplex®
Vitabase
Super Fat Burner
Vitabase
SuperZymes
Pure Encapsulations
Systemic Enzyme Complex
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive ®-EZ Swallow
Douglas Laboratories
Ultra Preventive® X
Vitabase
Ultra Veggie Enzymes
Pure Encapsulations
Uric Acid Formula
Thorne
Whey Protein Isolate Chocolate NSF
Thorne
Whey Protein Isolate Vanilla NSF
Douglas Laboratories
Wobenzym ® N
Douglas Laboratories
Wobenzym ® N
Douglas Laboratories
Wobenzym ® N
Douglas Laboratories
Wobenzym ® Plus
Douglas Laboratories
Wobenzym ® Plus
Douglas Laboratories
Wobenzym ® Plus
Douglas Laboratories
Wobenzym ® PS
Douglas Laboratories
Wobenzym ® PS