Evidence supporting the use of: Nettle (mixed)
For the health condition: Rhinitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Nettle (Urtica dioica), commonly referred to as stinging nettle, has been traditionally used for a variety of inflammatory conditions, including rhinitis (especially allergic rhinitis, or hay fever). In recent years, limited scientific research has been conducted to investigate its potential for supporting rhinitis. Several small clinical trials and in vitro studies suggest that nettle extracts may exert anti-inflammatory effects by inhibiting histamine receptors and interfering with inflammatory pathways relevant to allergic responses.

For example, a single-blind study published in 1990 found that 58% of participants with allergic rhinitis reported symptom relief after using freeze-dried nettle leaf. Some laboratory studies indicate that nettle can modulate key inflammatory mediators, such as prostaglandins and leukotrienes, which are involved in allergic rhinitis. However, these studies are generally small, short-term, and sometimes lacking placebo controls. Systematic reviews and guidelines acknowledge nettle as a possible complementary therapy but frequently stress the need for larger, well-designed randomized controlled trials to confirm both efficacy and safety.

In summary, while there is some scientific evidence supporting the use of nettle for rhinitis, the quality and quantity of data are limited. Its use is supported more by preliminary clinical and mechanistic studies than by robust clinical trial data, resulting in a modest evidence rating.

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Products containing Nettle (mixed)

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