Evidence supporting the use of: Alkanna
For the health condition: Scars / Scar Tissue
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Alkanna, particularly Alkanna tinctoria, has a long history of use in traditional herbal medicine for wound healing and the treatment of scars and scar tissue. In various cultures, the root—often called “alkanet”—has been used topically in the form of salves or oils. Its principal active compound is alkannin, a naphthoquinone derivative, which imparts a characteristic red color and is believed to have anti-inflammatory and antimicrobial properties. Historical accounts, especially from Mediterranean and Middle Eastern folk medicine, describe the use of Alkanna root preparations to promote skin healing, soothe irritation, and potentially minimize the appearance of scars. However, while there is some in vitro and animal research suggesting that alkannin may support wound healing and have antimicrobial effects, direct clinical evidence for its effectiveness in treating or reducing established scars or scar tissue in humans is currently lacking. The majority of support for using Alkanna in this context is therefore based on traditional practice rather than robust scientific validation. As such, its use for this purpose is best considered as traditional, with a modest evidence rating due to limited mechanistic and preclinical studies but a lack of clinical trials.
Other ingredients used for Scars / Scar Tissue
AcemannanAchyranthes
Alkanna
Allantoin
Aloe vera
Alpha hydroxy acids
argan nut oil
asiaticoside
banyan
bee propolis
Brazilian peppertree
Calotropis gigantea
Cedrus libani
Centella asiatica
Centella triterpenes
collagen
Connective tissue growth factor
copaiba oil
Cyathula
Davilla rugosa
dragon\'s blood
emu oil
Ficus religiosa
Galbanum
Glycolic acid
Glycosaminoglycans
gotu kola
henna
hyaluronic acid
Hyaluronidase
Indian nightshade
jojoba oil
Kigelia africana
L-proline
Myrobalan
oriental arborvitae
Panthenol
proteolytic enzymes
Rubia cordifolia
silicon
Silk protein
Sweet Bay
Tea Tree Oil
turmeric
vitamin C
vitamin E
Witch Hazel
Zinc
