Evidence supporting the use of: Aloe Polysaccharide
For the health condition: Scars / Scar Tissue

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aloe polysaccharides, primarily derived from the inner gel of Aloe vera leaves, have a long history of traditional use in the topical treatment of skin wounds, burns, and scars. Historical medical texts and folk medicine traditions from various cultures report the use of Aloe vera gel to soothe skin irritation and promote healing, which includes the management of scar tissue. The polysaccharides in Aloe vera, such as acemannan, are believed to contribute to skin hydration, anti-inflammatory effects, and possibly promote the proliferation of fibroblasts—cells involved in wound healing and scar formation. However, while some in vitro and animal studies suggest that Aloe polysaccharides may modulate inflammation and enhance collagen synthesis, direct scientific evidence specifically validating the efficacy of Aloe polysaccharide for reducing or treating established scars or scar tissue in humans is limited and inconsistent. Most clinical studies focus on wound healing rather than scar remodeling, and results are mixed. Thus, its use for scars is primarily supported by traditional application and anecdotal evidence rather than robust, high-quality clinical trials targeting scar outcomes.

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Products containing Aloe Polysaccharide

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