Evidence supporting the use of: Alpha hydroxy acids
For the health condition: Scars / Scar Tissue

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha Hydroxy Acids (AHAs) are a group of naturally occurring acids commonly used in skincare, most notably glycolic acid and lactic acid. Their primary mechanism is exfoliation: by loosening the bonds between dead skin cells, AHAs promote desquamation and encourage the growth of new, healthy skin. In the context of scars and scar tissue, especially superficial or post-acne scarring, AHAs can improve skin texture and pigmentation irregularities. Several small clinical studies and case reports have shown that regular topical application of AHAs (usually glycolic acid at concentrations of 10-20%) can lead to modest improvements in the appearance of mild atrophic (depressed) scars, such as those left by acne, due to enhanced epidermal turnover and stimulation of collagen production in the dermis. However, evidence for significant improvement of more severe or hypertrophic (raised) scars is limited, with most studies focusing on cosmetic outcomes rather than histological changes.

While AHAs are a mainstay in cosmetic dermatology for improving skin tone and texture and are sometimes recommended as part of a regimen for treating superficial scars, their effectiveness is generally rated as moderate and mostly for mild or early-stage scars. There is insufficient high-quality, large-scale evidence to support their use as a primary treatment for deep or complex scar tissue. Thus, while some scientific evidence exists, the overall level of support is modest, and AHAs are considered an adjunct rather than a main therapy for scarring.

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Products containing Alpha hydroxy acids

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