Evidence supporting the use of: Panthenol
For the health condition: Scars / Scar Tissue

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Panthenol, also known as provitamin B5, is commonly included in topical formulations aimed at supporting skin healing, hydration, and barrier repair. Its use for scars and scar tissue is supported by some scientific evidence, though this evidence is generally limited and of low to moderate quality. Panthenol is known to improve skin hydration and elasticity, which may indirectly support the healing environment and reduce the appearance of scar tissue. Some in vitro and animal studies suggest that panthenol can promote fibroblast proliferation and accelerate wound healing processes. Small clinical studies and case reports indicate improvements in skin softness, redness, and itching in healed scars when panthenol-containing products are used. However, there is a lack of large randomized controlled trials specifically evaluating panthenol’s effect on established scar tissue or its efficacy in preventing hypertrophic or keloid scarring. As such, while panthenol is a safe and well-tolerated ingredient with plausible mechanisms for supporting normal skin healing, its direct benefit for scar remodeling or significant scar reduction remains insufficiently supported by strong clinical evidence. Its use is more commonly justified as an adjunct in moisturizing and soothing the skin during the healing process rather than as a primary scar treatment.

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Products containing Panthenol

We currently have no products on Vitabase that contain this ingredient.