Evidence supporting the use of: Allantoin
For the health condition: Scratches and Abrasions

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allantoin is commonly used in topical formulations for minor skin injuries such as scratches and abrasions. The support for its use is primarily based on its documented ability to promote wound healing and its keratolytic (skin-softening) properties. Scientifically, allantoin is known to enhance cell proliferation and encourage epithelialization—the process by which new skin cells form over a wound. Several in vitro and animal studies have demonstrated that allantoin can stimulate tissue regeneration and accelerate wound closure. Additionally, allantoin exhibits moisturizing and soothing effects, which can help reduce irritation and discomfort associated with superficial skin injuries.

However, high-quality clinical trials in humans specifically evaluating allantoin’s efficacy for scratches and abrasions are limited. Most evidence comes from laboratory studies, animal models, or observational reports. Regulatory agencies such as the FDA recognize allantoin as a skin protectant and allow its use in over-the-counter products for minor cuts, scrapes, and burns, which provides some level of endorsement. Despite this, the overall clinical evidence is modest, and more robust, controlled human studies are needed to conclusively establish its effectiveness for this specific indication.

In summary, while there is some scientific rationale and preclinical data supporting the use of allantoin for scratches and abrasions, the quality and quantity of direct clinical evidence are limited, meriting a moderate evidence rating.

More about Allantoin
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Products containing Allantoin

We currently have no products on Vitabase that contain this ingredient.