Stone Root (Collinsonia canadensis) has a history of traditional use among Native American and early European settlers in North America as a herbal remedy, primarily for conditions affecting the veins, such as hemorrhoids and varicose veins, as well as for urinary and digestive complaints. Its use for scratches and abrasions is less well-documented, but some sources note that Stone Root was occasionally applied topically for minor wounds, sores, and skin irritations. The rationale for this traditional use may be connected to its purported astringent and anti-inflammatory properties, which were believed to help tighten tissues and reduce irritation.

There is, however, little to no robust scientific evidence supporting the effectiveness of Stone Root in treating scratches or abrasions. No clinical trials or rigorous pharmacological studies have evaluated its effects specifically on wound healing or skin repair. Most references to its use for skin conditions are anecdotal or based on historical herbal texts, rather than modern scientific validation. Thus, while Stone Root may have a limited tradition of use for minor skin injuries, this is not strongly backed by scientific data.