Evidence supporting the use of: Terpinen-4-ol
For the health condition: Scratches and Abrasions

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Terpinen-4-ol is the primary active component of tea tree oil (Melaleuca alternifolia). Its use for minor skin injuries such as scratches and abrasions is supported by scientific evidence, primarily due to its antimicrobial and anti-inflammatory properties. Several in vitro and clinical studies have demonstrated that terpinen-4-ol exhibits broad-spectrum antibacterial activity, including efficacy against Staphylococcus aureus and other skin pathogens. This antimicrobial action can help reduce the risk of infection in superficial wounds.

Additionally, terpinen-4-ol has been shown to modulate inflammatory responses by suppressing pro-inflammatory cytokines, which may aid in reducing redness and swelling commonly associated with minor skin injuries. Some small clinical trials and case reports have indicated that topical preparations containing tea tree oil (and by extension, terpinen-4-ol) can promote wound healing and reduce infection rates, though direct studies on terpinen-4-ol alone are limited.

However, while the evidence is promising, most clinical studies have used whole tea tree oil rather than isolated terpinen-4-ol. As such, the overall quality and quantity of evidence supporting terpinen-4-ol alone for scratches and abrasions is moderate, justifying a rating of 3. Properly formulated products should be used to avoid skin irritation or allergic reactions, as higher concentrations of terpinen-4-ol can sometimes cause dermatitis in sensitive individuals.

More about Terpinen-4-ol
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Products containing Terpinen-4-ol

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