Evidence supporting the use of: Lion's mane
For the body system: Senses

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Source of validity: Scientific
Rating (out of 5): 3

Lion’s Mane and the Senses Body System: Scientific Evidence

Lion’s mane (Hericium erinaceus) is a medicinal mushroom traditionally used in East Asia for general health and cognitive support. Recent scientific research has focused on its neuroprotective and neuroregenerative properties, which are relevant to the Senses body system, especially regarding nerve health and function.

Several preclinical studies demonstrate that lion’s mane extracts contain compounds (hericenones and erinacines) that can stimulate nerve growth factor (NGF) synthesis. NGF is crucial for the maintenance and regeneration of neurons, including those involved in sensory perception. Animal studies have shown that lion’s mane supplementation can improve nerve regeneration after injury and enhance sensory and motor function. For example, a 2013 study found that lion's mane promoted peripheral nerve regeneration in rats after crush injury.

In humans, evidence is still emerging. Small clinical trials have shown cognitive benefits in older adults with mild cognitive impairment, but direct investigations into sensory function (such as vision, hearing, or touch) are lacking. However, the mechanisms by which lion’s mane supports nerve health could plausibly benefit sensory nerves. More rigorous, targeted human studies are needed to directly establish its efficacy for the Senses body system.

In summary, there is moderate scientific evidence from animal and in vitro studies for lion’s mane supporting nerve health, which may relate to the senses, but direct clinical proof for sensory improvement is limited.

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