Evidence supporting the use of: Menthol
For the body system: Senses

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Menthol is widely recognized for its effects on the Senses body system, particularly in relation to its impact on sensory perception and the nervous system. Scientific studies have demonstrated that menthol acts on the transient receptor potential melastatin 8 (TRPM8) ion channels, which are involved in the detection of cold sensations. When applied topically or inhaled, menthol produces a cooling sensation by activating these receptors in the skin and mucous membranes, leading to an enhanced perception of coolness without an actual drop in temperature. This property is exploited in products designed to relieve minor throat irritation, nasal congestion, and headaches, where menthol’s sensory-modulating effects help provide symptomatic relief.

There is also evidence that menthol’s sensory effects can improve subjective feelings of airflow in conditions like nasal congestion, even though objective measures of airflow may not change significantly. In addition, menthol is used in oral hygiene products for its ability to provide a fresh sensation and mask unpleasant odors, further supporting its association with the senses. While most research supports menthol’s efficacy for sensory modulation rather than treatment of underlying disease, its repeated and validated use in clinical and over-the-counter products justifies a high evidence rating (4/5) for its support of the Senses body system.

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Products containing Menthol

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