Evidence supporting the use of: N-Acetyl Carnosine
For the body system: Senses
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
N-Acetyl Carnosine (NAC) is most commonly used in the context of supporting the Senses body system, particularly eye health. NAC is a derivative of carnosine that is more stable and able to penetrate the cornea, making it a candidate for use in eye drops. Several small-scale clinical studies, mainly conducted in Russia and Eastern Europe, have evaluated NAC eye drops for their potential to slow the progression of cataracts and reduce lens opacification. These studies suggest that NAC may act as an antioxidant, reducing oxidative stress in the lens, which is a known factor in cataract development. However, the quality of the evidence is limited: most studies are small, of short duration, and lack rigorous controls. There is little research supporting its use for senses other than vision. Regulatory agencies such as the FDA have not approved NAC for any ophthalmic indication, and major ophthalmological associations do not recommend its use due to insufficient evidence. In summary, while there is some preliminary scientific support for the use of N-Acetyl Carnosine in eye health, particularly for cataract prevention or management, the evidence is limited and not widely accepted in mainstream medicine. Its use for other sensory systems is not supported by scientific or traditional evidence.