Evidence supporting the use of: Brahmi
For the body system: Serotonin

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Brahmi (Bacopa monnieri) is traditionally used in Ayurvedic medicine as a cognitive enhancer and adaptogen. Scientific interest in Brahmi has grown in recent decades, with preclinical and clinical studies investigating its effects on neurotransmitter systems, including serotonin. Several animal studies have suggested that Brahmi extracts can modulate serotonin levels in the brain, with effects similar to those of certain antidepressants. For example, rodent models have shown increased serotonin in the hippocampus and cortex after Brahmi administration, potentially contributing to its anxiolytic and antidepressant effects.

Some human studies have explored Brahmi's effects on mood and cognitive function. Randomized controlled trials indicate that Brahmi supplementation may reduce symptoms of anxiety and mild depression, which are associated with serotonin regulation. However, direct evidence in humans linking Brahmi to measurable increases in serotonin or direct modulation of the serotonergic system is limited. Most clinical trials assess subjective mood and cognitive outcomes rather than biochemical markers.

In summary, while preclinical research provides a plausible mechanistic link between Brahmi and serotonin modulation, and some clinical studies support mood benefits, the evidence for direct, robust support of the "serotonin body system" in humans is moderate. More research, especially well-designed human trials measuring neurotransmitter changes, is needed for a stronger evidence base.

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