Evidence supporting the use of: Convolvulus prostratus
For the body system: Serotonin

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Convolvulus prostratus, also known as Shankhpushpi, is an herb widely used in traditional Ayurvedic medicine for its purported effects on the brain and nervous system. In Ayurveda and some other traditional systems, it is classified as a "Medhya Rasayana"—a rejuvenative for cognitive function and mental health. Its use for mood enhancement and support of neurotransmitter balance, including serotonin, is based on these traditional concepts. There is limited preclinical research suggesting that Convolvulus prostratus may have neuroprotective, anxiolytic, and antidepressant-like effects, potentially via modulation of neurotransmitters like serotonin, dopamine, and norepinephrine. However, these studies are largely in animal models and do not provide direct evidence in humans, nor do they conclusively establish a mechanism involving serotonin regulation. There are no large-scale clinical trials or systematic reviews confirming its efficacy for serotonin-related disorders in humans. Thus, its use for "supporting the serotonin body system" is justified primarily by tradition, with only weak scientific support at this time.

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