Evidence supporting the use of: Jatamansi
For the body system: Serotonin

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jatamansi (Nardostachys jatamansi) is a traditional herb extensively used in Ayurvedic and other traditional medicine systems. It has a long history of use for its calming, sedative, and mood-stabilizing effects. Traditionally, Jatamansi has been employed to address issues related to stress, anxiety, and insomnia, which are often linked with neurotransmitter systems such as serotonin. Some Ayurvedic texts describe its use in balancing the mind and promoting emotional well-being, suggesting its indirect influence on what modern science identifies as the serotonin system.

While there are preclinical studies suggesting that extracts of Jatamansi may influence neurotransmitters like serotonin and dopamine in animal models, robust clinical evidence in humans is lacking. Most studies are either in vitro or performed on rodents, indicating possible antidepressant-like effects and modulation of the serotonergic system. However, these findings have not yet translated into strong, reproducible clinical trials in humans.

In summary, the use of Jatamansi to support the serotonin system is primarily rooted in traditional practices, with limited preclinical scientific support but insufficient high-quality human data. The evidence rating is therefore 2, reflecting that while there is a historical precedent and some biological plausibility, strong scientific validation is not yet established.

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