Evidence supporting the use of: Vitamin B6 (various)
For the body system: Serotonin

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B6 (pyridoxine) is scientifically recognized for its role in supporting the serotonin system in the body. Vitamin B6 acts as a coenzyme in the biosynthesis of several neurotransmitters, including serotonin. Specifically, it is required for the conversion of the amino acid tryptophan into 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated to form serotonin. Multiple studies have demonstrated that Vitamin B6 deficiency can lead to reduced serotonin synthesis and that supplementation may normalize neurotransmitter levels. Clinical trials and biochemical research support the role of B6 in mood regulation, with some evidence suggesting that B6 supplementation may have a modest benefit for depressive symptoms, possibly due to its effect on serotonin production. However, while the connection between B6 and serotonin synthesis is well-established biochemically, the translation to significant clinical outcomes in mood disorders is still under investigation. Overall, there is substantial scientific validation for B6’s role in serotonin metabolism, earning it a high evidence rating for supporting the serotonin body system, though not the maximum, given the need for more robust clinical trial data for specific therapeutic claims.

More about Vitamin B6 (various)
More about Serotonin

Products containing Vitamin B6 (various)

We currently have no products on Vitabase that contain this ingredient.