Evidence supporting the use of: Ephedra
For the health condition: Sinus Infection
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Ephedra (known as Ma Huang in traditional Chinese medicine) has a long history of use in East Asian herbal practice for respiratory conditions, including sinus congestion and infections. The plant contains active compounds called ephedrine alkaloids, which have sympathomimetic effects—meaning they stimulate the nervous system in a way similar to adrenaline. This leads to vasoconstriction (narrowing of blood vessels) in the nasal passages, which can reduce swelling and improve airflow, offering symptomatic relief from nasal congestion. While this mechanism supports its use for sinus-related symptoms, clinical studies specifically evaluating Ephedra for sinus infections are limited. Most scientific literature focuses on its decongestant effects rather than its ability to treat the underlying infection. Safety concerns over cardiovascular and central nervous system side effects have led to regulatory restrictions on Ephedra-containing supplements in many countries. Thus, while its use for sinus congestion is well-established in traditional medicine and supported by its pharmacological action as a decongestant, strong clinical evidence for its efficacy in treating sinus infections is lacking. This places its use primarily in the realm of traditional rather than scientifically validated medicine, with a moderate level of evidence for symptomatic relief but not for curing infections themselves.
Other ingredients used for Sinus Infection
alpha-pinenebenegut perilla (proprietary)
black pepper
bromelain
echinacea purpurea
elderberry
fennel
goldenseal
immunoglobin G
honeysuckle
lactobacillus gasseri
marshmallow
mint
Peppermint
platycodon root
quercetin
serratiopeptidase
slippery elm bark
vitamin C
Wasabi
zinc
mullein
hyssop
cardamom
malabar nut
inula racemosa
anise
pau d'arco
elecampane
sweetgums
Sichuan pepper
sea salt
Anamarrhena
Alpha-terpineol
Asarum heterotropoides
Asafoetida
Andrographis
Allyl isothiocyanate
Barleria
black salt
Buddha's Hand
Cineole
Cinidium
Cistus
cypress
Ephedra
Elder
Eyebright
Frankincense
Goldthread
Gardenia jasminoides
Heartsease
Homalomena
Honey loquat syrup
Liverwort
Mentha haplocalyx
Marjoram
Matapalo Tree
Mucolase
Premna
Pinellia Ternata
Platycodon
Pelargonium
Piper retrofractum
Pimpinella
Ravinsara
Speedwell
Savory
Sweet Bay
Sargassum
Vasicine