Evidence supporting the use of: Goldthread
For the health condition: Sinus Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldthread (Coptis chinensis) is a herb traditionally used in Chinese medicine for a variety of ailments, including infections and inflammation. Its primary active compound, berberine, has demonstrated antimicrobial and anti-inflammatory properties in laboratory studies. Historically, Goldthread has been used to "clear heat" and "dry dampness," concepts in Traditional Chinese Medicine (TCM) often associated with infection and phlegm in the respiratory tract, including sinus congestion and sinusitis.

However, while the traditional use for sinus infection and related upper respiratory tract conditions is well-established, scientific validation for its efficacy in treating sinus infections specifically is limited. Some in vitro and animal studies support the antimicrobial activity of berberine against pathogens that can cause sinus infections, but high-quality clinical trials in humans are lacking. As such, while there is a plausible basis for its use rooted in tradition and some preliminary biological rationale, there is insufficient scientific evidence to fully endorse Goldthread as an effective treatment for sinus infections.

In summary, Goldthread's use in sinus infection is primarily justified by traditional use, with a modest level of preliminary scientific support, but lacks robust clinical evidence.

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