Evidence supporting the use of: Lactobacillus gasseri
For the health condition: Sinus Infection

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus gasseri is a probiotic bacterium that has gained attention for its potential role in supporting sinus health, particularly in the context of sinus infections (rhinosinusitis). The justification for its use is based on emerging scientific studies rather than long-standing traditional use. The evidence is still preliminary and limited, so the overall rating is 2 out of 5.

Several small clinical studies and pilot trials have investigated the application of L. gasseri in patients with chronic rhinosinusitis. One notable double-blind, placebo-controlled study demonstrated that nasal sprays containing L. gasseri improved symptoms and quality of life in patients with chronic rhinosinusitis without nasal polyps. The hypothesized mechanism is that L. gasseri may help restore a healthy microbial environment in the sinonasal passages, inhibit the growth of pathogenic bacteria (like Staphylococcus aureus), and modulate local immune responses.

However, the sample sizes in these studies are small, and there is a lack of large, well-powered randomized controlled trials. Additionally, the duration of follow-up is often short, and the optimal delivery method (oral vs. nasal administration) is still under investigation. There is little to no historical or traditional use of this probiotic for sinus infections—it is a modern, research-driven application.

In summary, while L. gasseri shows promise for supporting sinus health and possibly reducing symptoms of sinus infection, more robust scientific evidence is needed before it can be considered an established treatment.

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