Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Malabar nut (Justicia adhatoda), also known as Vasaka, has a long history of use in traditional Ayurvedic and Unani medicine for treating various respiratory ailments, including cough, bronchitis, and sinus congestion. The leaves contain active compounds such as vasicine and vasicinone, which exhibit bronchodilator, expectorant, and mild anti-inflammatory properties. In traditional systems, decoctions or extracts of Malabar nut are often prescribed for "sinusitis" or to relieve symptoms of blocked sinuses, nasal discharge, and related headaches. Most of the support for its use in sinus infection comes from these historical and empirical applications rather than from rigorous modern clinical trials specifically targeting sinus infection. A limited number of preclinical studies suggest that Malabar nut extracts can reduce airway inflammation and mucus production in animal models, but few, if any, clinical studies have been conducted directly on patients with sinusitis. A handful of in vitro and animal studies support its potential to inhibit some bacteria and respiratory pathogens, possibly offering ancillary benefits for upper respiratory infections. However, there is insufficient modern scientific evidence to conclusively support its efficacy specifically for sinus infections in humans. Thus, its use for sinus infection is primarily justified by a tradition of use, with only modest preclinical scientific support for its respiratory benefits.

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