Evidence supporting the use of: European elderberry constituents (unspecified)
For the body system: Sinuses
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
European elderberry (Sambucus nigra) has a long history of use in traditional herbal medicine, particularly for supporting respiratory health, including sinus-related complaints. More recently, scientific interest has focused on its bioactive constituents, such as flavonoids (including quercetin and anthocyanins) and triterpenes, which have demonstrated antioxidant, anti-inflammatory, and antiviral properties in laboratory and animal models. A few small human clinical trials and observational studies have shown that elderberry extracts may reduce the duration and severity of symptoms in upper respiratory tract infections, such as the common cold and influenza. These effects are thought to be partly due to the inhibition of viral replication and modulation of cytokine production, which could indirectly benefit the sinuses by reducing inflammation and congestion.
However, while there is moderate scientific evidence supporting elderberry's role in alleviating general upper respiratory symptoms, direct research specifically targeting sinus health (e.g., sinusitis) is limited. Most studies do not isolate sinus outcomes from broader respiratory symptoms. Therefore, while the use of elderberry constituents for supporting the sinuses is partially justified by scientific evidence, the evidence is not robust or highly specific. More targeted clinical research is needed to confirm its efficacy for sinus health.
More about European elderberry constituents (unspecified)
More about Sinuses
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Other body systems supported by European elderberry constituents (unspecified)
BloodDigestive System
Gastrointestinal Tract
Immune System
Intestinal System
Lungs
Respiratory System
Sinuses
Skin