Evidence supporting the use of: Serrapeptase
For the body system: Sinuses
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Serrapeptase is a proteolytic enzyme originally isolated from bacteria in the intestines of silkworms. It has been used, particularly in Europe and parts of Asia, as a supplement aimed at reducing inflammation and supporting sinus health. The scientific basis for its use in sinus support comes from its proposed ability to break down protein-based debris, thin mucus, and reduce inflammation, which could theoretically help clear the sinuses and relieve symptoms of sinusitis.
Some clinical studies have evaluated Serrapeptase in the context of ENT (ear, nose, and throat) conditions. For example, a few small trials from the 1980s and 1990s reported reduced swelling, improved mucociliary clearance, and decreased viscosity of nasal mucus in patients with chronic sinusitis or after sinus surgery. However, these studies tend to be limited in size, quality, and often lack rigorous controls. Systematic reviews generally conclude that while there is some evidence of benefit, it is weak and further high-quality research is needed to confirm effectiveness and safety.
Overall, the use of Serrapeptase for sinus support is based on plausible mechanisms and preliminary clinical evidence, but it lacks strong, large-scale scientific validation. Regulatory agencies do not currently endorse its use for this purpose, and more research is needed before firm conclusions can be drawn.
Other ingredients that support Sinuses
alpha-pinenebasil
bayberry
radish
bromelain
chamomile
turmeric
elderberry
fennel
garlic bulb
ginger
goldenseal
onion
horseradish
lactobacillus salivarius
lemon
licorice root
marshmallow
mint
spruce
oregano
peppermint oil
perilla
pineapple
plantain
platycodon root
purple butterbur root
quercetin
sage
schizonepeta
serratiopeptidase
thyme
vitamin C
water
xylitol
zhejiang fritillary
zinc
boneset
mullein
catnip
xanthium (cockleburs)
lobelia
capsicum
malabar nut
anise
tylophora
lingzhi
yarrow
fritillaria
lemongrass
yerba santa
elecampane
sodium salt
coltsfoot
sweet flag
eucalyptus
menthol oil
aster root
wood betony
horehound
herbal blend (proprietary)
cayenne pepper
Allicin
Asarum heterotropoides
Asarabacca
Arisaema
Asarum sieboldii
Bee Propolis
Betony
Baikal Skullcap
Boswellia
Butterbur
Bee products
Buddha's Hand
Balloon Flower
Carvacrol
Citrus
Cineole
Cajuput
Centipeda
Cubeb
Cowslip
Calamus
Cocklebur
European Elder
English Horsemint
Echinacea
Elder
Goldthread
Garlic
Other body systems supported by Serrapeptase
ArteriesBlood
Bronchials
Circulatory System
Lungs
Mucus Membranes
Sinuses