Evidence supporting the use of: Calcium Bisphosphonate
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Calcium bisphosphonate is not a single compound, but rather refers to a class of medications called bisphosphonates (such as alendronate, risedronate, ibandronate) that are often used in conjunction with adequate calcium intake to support bone health. Bisphosphonates are scientifically validated for their use in the treatment and prevention of osteoporosis and other conditions that result in bone loss. These compounds work by inhibiting osteoclast-mediated bone resorption, thereby reducing bone turnover and increasing bone mineral density. Numerous large, randomized controlled trials and meta-analyses have demonstrated that bisphosphonates significantly reduce the risk of vertebral, nonvertebral, and hip fractures in postmenopausal women and others at risk of osteoporosis.

The use of calcium supplementation alongside bisphosphonate therapy is also well-established, as adequate calcium (and vitamin D) is necessary for optimal bone health and for the efficacy of bisphosphonates. Clinical guidelines from organizations such as the National Osteoporosis Foundation and the American College of Physicians recommend bisphosphonates as first-line therapy for osteoporosis. The evidence base for their efficacy and safety profiles is extensive, with decades of research supporting their role in maintaining and improving skeletal system health.

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Other body systems supported by Calcium Bisphosphonate

Skeletal System (Bones)

Products containing Calcium Bisphosphonate

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