Evidence supporting the use of: Calcium Potassium Phosphate Citrate
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Calcium Potassium Phosphate Citrate is a mineral complex sometimes used in dietary supplements targeting bone health. The scientific rationale for its use centers on the key roles of its constituents—calcium, phosphate, and potassium—in bone metabolism. Calcium and phosphate are the primary mineral components of bone, forming hydroxyapatite crystals that give bone its strength and structure. Calcium supplementation is strongly supported by evidence for the maintenance of bone density and the prevention of osteoporosis, especially in populations at risk of deficiency. Phosphate is also essential for bone mineralization, though less commonly a limiting nutrient in most diets.

Potassium citrate has been shown in some studies to reduce urinary calcium excretion and may help neutralize dietary acid load, which can otherwise promote bone resorption. Clinical trials have suggested that potassium citrate may help preserve bone mineral density, particularly in postmenopausal women, though the evidence is not as robust as that for calcium.

The combined form, "calcium potassium phosphate citrate," is less frequently studied as a single compound in peer-reviewed research, so direct evidence for this exact combination is limited. However, the individual components have scientific backing for roles in supporting the skeletal system, justifying its inclusion in bone health supplements. The overall evidence level is moderate due to the extrapolation from individual components rather than from robust trials of the compound itself.

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Other body systems supported by Calcium Potassium Phosphate Citrate

Skeletal System (Bones)
Teeth

Products containing Calcium Potassium Phosphate Citrate

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