Evidence supporting the use of: Cartilage
For the body system: Skeletal System (Bones)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cartilage is a connective tissue found in various parts of the body, including joints, the rib cage, ear, nose, bronchial tubes, and intervertebral discs. Its role in directly supporting the skeletal system is well-established anatomically, as it provides cushioning, reduces friction, and enables smooth articulation between bones. In the context of supplementation or therapeutic interventions (such as bovine or shark cartilage supplements), the evidence supporting its efficacy in improving skeletal health, specifically bone strength or joint health, is limited and mixed. Some research has explored the use of cartilage-derived supplements for osteoarthritis and joint pain, but clinical trials have generally shown inconsistent or minimal benefits compared to placebo. The structural proteins and compounds found in cartilage—such as collagen and glycosaminoglycans—are believed to contribute to joint health, but these effects are better supported for isolated compounds (like glucosamine or chondroitin) rather than whole cartilage supplements. Therefore, while cartilage is scientifically recognized as a crucial component of the skeletal system's function, scientific validation for supplementing with cartilage to support skeletal health is weak, warranting a modest evidence rating.
Other ingredients that support Skeletal System (Bones)
AchyranthesAlfalfa
Algae
Algas calcareas
alpha-ketoglutarate (AKG)
amino acids
animal protein
antler
arugula
baicalein
beef
bone marrow
bone protein
boneset
boron
Boswellia
Boswellic Acid
bovine
bovine cartilage / glycosaminoglycan
bovine protein
broccoli
Buckwheat
calcium
cartilage
Chinese mountain ant
Chinese pond turtle
Chinese salvia root
Chinese silkvine
chondroitin
chuchuhuasi
Cissus quadrangularis
citrate malate
cod liver oil
collagen
collard
comfrey
Corallina officinalis
cruciferous
daidzein
deer velvet
devil's claw
Dipsacus
dolomite
Drynaria
egg
elk antler
estrogen
eucommia
Eucommia ulmoides
fibroblast growth factor
fish
fish protein
Foxtail millet
fructoborate
genistein
genistin
Glycosaminoglycans
green-lipped mussel
herbal blend (proprietary)
HMB hydroxymethylbutyrate
horse gram
horsetail
hydroxyproline
icariin
Indian frankincense
ipriflavone
isoflavones
Kaempferol
Ledebouriella
Legume protein
Lithothamnion
magnesium
manganese
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk
Milk Protein
Mineral blend
Molasses
Osthole
Peptides
phosphorus
Phytoestrogens
Polygonatum
protein
proteoglycans
prune
Rehmannia
rehmannia glutinosa
seaweed
sesame
Shilajit
silicon
Sinomenium acutum
solomon's seal
Soy
soy isoflavones
Soy Protein
Spatholobus
spinach
strontium
Taxillus chinensis
Taxillus sutchuenensis
trace minerals
vitamin C
vitamin D
vitamin D3
vitamin K
Products containing cartilage
Pure Encapsulations
Joint Complex
Pure Encapsulations
Joint Complex
Metagenics
OsteoVantiv®
Metagenics
Ostera®
