Evidence supporting the use of: Collagen
For the body system: Skeletal System (Bones)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Collagen is scientifically validated as an important component in supporting the skeletal system, particularly bones. Collagen is the most abundant protein in the human body, and approximately 90% of the organic matrix of bone is composed of type I collagen. This collagen matrix provides tensile strength and a scaffold for mineralization, which is crucial for bone strength and structure. Scientific studies, including randomized controlled trials, have shown that oral collagen supplementation can positively affect bone metabolism. For example, research has demonstrated that collagen peptides can stimulate osteoblast activity (cells responsible for bone formation), increase bone mineral density, and reduce bone degradation markers, especially in postmenopausal women who are at increased risk for osteoporosis.

A 2018 randomized, double-blind, placebo-controlled trial published in Nutrition found that daily collagen peptide supplementation increased bone mineral density in postmenopausal women with age-related bone loss. Additional in vitro and animal studies support these findings, showing enhanced bone formation and reduced bone resorption with collagen supplementation. However, while results are promising, more large-scale and long-term human trials are needed to fully establish the efficacy and optimal dosing. Overall, current scientific evidence supports the use of collagen for bone health, meriting a high (but not perfect) evidence rating.

More about collagen
More about Skeletal System (Bones)