Evidence supporting the use of: Green-lipped mussel
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Green lipped mussel (Perna canaliculus) is primarily used to support joint health, which is closely related to the skeletal system. There is scientific evidence suggesting that extracts from green lipped mussel possess anti-inflammatory properties and may help reduce symptoms associated with osteoarthritis and rheumatoid arthritis, both of which affect the skeletal system. Several clinical trials and animal studies have reported that supplementation with green lipped mussel can reduce joint pain, stiffness, and improve mobility in individuals with osteoarthritis, likely due to the presence of omega-3 fatty acids (notably EPA and DHA), glycosaminoglycans, and other bioactive compounds.

A 2018 systematic review (Brien et al., BMC Complement Altern Med.) concluded that green lipped mussel supplementation has a modest but significant effect on reducing pain and improving function in osteoarthritis patients. However, the effects appear to be more substantial for joint cartilage and connective tissues rather than directly on bone density or bone health. The evidence base is moderate, with some studies showing positive outcomes and others showing minimal effect, and most research focuses on joint health rather than direct support for bone structure or density.

In summary, while there is scientific evidence supporting the use of green lipped mussel for joint-related aspects of the skeletal system, the evidence for direct effects on bone health is limited. The overall rating for its use in supporting the skeletal system, particularly bones, is 3/5 based on current scientific literature.

More about green-lipped mussel
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Other body systems supported by green-lipped mussel

Immune System
Joints
Skeletal System (Bones)