Evidence supporting the use of: Ligandrol
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ligandrol (also known as LGD-4033) is a selective androgen receptor modulator (SARM) that has been investigated for its potential to support the skeletal system, specifically by promoting bone health. Scientific studies have shown that androgens (such as testosterone) play a key role in maintaining bone mineral density and stimulating bone formation. Ligandrol, as a SARM, selectively binds to androgen receptors in muscle and bone, mimicking some of the effects of anabolic steroids but with fewer side effects.

Preclinical studies in animal models have demonstrated that Ligandrol can increase bone mineral density and strength, likely due to its anabolic effects on bone tissue. A phase I clinical trial in healthy men (Baseline et al., 2013) showed that LGD-4033 increased lean body mass and was well-tolerated over a short duration, but this study did not directly measure bone outcomes. Other early-phase studies suggest potential benefits for conditions involving muscle and bone loss, such as osteoporosis or age-related sarcopenia, but comprehensive human data specific to bone health are limited.

In summary, while there is a scientific rationale and some preclinical evidence for Ligandrol's use in supporting the skeletal system, robust clinical evidence in humans is still lacking. Therefore, its use for bone health is supported by moderate scientific evidence, and further research is needed to fully establish its efficacy and safety for this purpose.

More about Ligandrol
More about Skeletal System (Bones)

Other body systems supported by Ligandrol

Muscles
Skeletal System (Bones)
Testosterone

Products containing Ligandrol

We currently have no products on Vitabase that contain this ingredient.