Relationship: Skeletal System (Bones) and manganese

Evidence supporting the use of: Manganese
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Manganese is a trace mineral that plays a significant role in bone health, providing scientific justification for its use in supporting the skeletal system. Biochemically, manganese is a cofactor for several enzymes involved in bone formation, including glycosyltransferases, which are required for the synthesis of proteoglycans that form the organic matrix of bone. Studies in animal models have shown that manganese deficiency leads to impaired bone growth, skeletal deformities, and reduced bone mineral density. In humans, observational studies suggest a correlation between adequate manganese intake and bone health, and low manganese levels have been associated with decreased bone mineral density in postmenopausal women. However, strong interventional data in humans are limited. While some small studies have included manganese as part of multi-mineral supplements (often with calcium, zinc, and copper) and shown modest improvements in bone markers or density, the individual contribution of manganese alone is less clear. The Institute of Medicine recognizes manganese as an essential nutrient for bone health, but deficiency is rare in healthy individuals consuming a typical diet. Overall, manganese's role in supporting the skeletal system is scientifically valid, but the strength of the evidence is moderate, justifying a rating of 3.

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Other ingredients that support Skeletal System (Bones)

alfalfa
alpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
Comfrey
Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Eucommia ulmoides
Estrogen
Fish
fibroblast growth factor
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein

Other body systems supported by manganese

Blood
Glandular System
Immune System
Joints
Mitochondria
Nerves
Skeletal System (Bones)
Skin

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Evidence supporting the use of: Manganese
For the body system: Skeletal System (Bones)

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Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by manganese

Products containing manganese

Health Concerns

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Evidence supporting the use of: ManganeseFor the body system: Skeletal System (Bones)

Table of Contents

Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by manganese

Products containing manganese

Evidence supporting the use of: Manganese
For the body system: Skeletal System (Bones)