Mineral blends, typically composed of essential minerals such as calcium, magnesium, phosphorus, and sometimes trace elements like zinc and copper, are scientifically validated for their role in supporting the skeletal system. Calcium is a primary structural component of bones and is necessary for maintaining bone density and strength. Magnesium contributes to bone formation by facilitating the conversion of vitamin D to its active form, which in turn aids calcium absorption. Phosphorus is a fundamental part of bone mineral matrix. Deficiencies in any of these minerals can lead to compromised bone health, including conditions such as osteoporosis and osteomalacia.

Numerous clinical studies and reviews have confirmed that adequate dietary intake of these key minerals supports bone mineral density and reduces the risk of bone-related diseases. For example, the National Institutes of Health and the World Health Organization recognize calcium and vitamin D (often co-formulated with mineral blends) as effective interventions for maintaining bone health. Supplementation is especially important in populations at risk of deficiency, such as postmenopausal women and the elderly.

However, while the evidence base is strong for individual minerals, the effectiveness of commercial "mineral blends" can vary based on formulation and bioavailability. Overall, the scientific consensus supports the use of mineral blends, particularly those containing calcium and magnesium, for skeletal system support.