Evidence supporting the use of: Vitamin D (cholecalciferol)
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D (cholecalciferol) is strongly supported by scientific evidence for its essential role in supporting the skeletal system. Vitamin D facilitates the intestinal absorption of calcium and phosphorus, minerals critical for the formation and maintenance of healthy bones. A deficiency in vitamin D impairs bone mineralization, leading to rickets in children—a condition characterized by bone deformities—and osteomalacia in adults, which results in soft, weak bones. Substantial clinical research demonstrates that adequate vitamin D intake, either through diet, supplementation, or sunlight exposure, is necessary to maintain normal bone density and prevent fractures, especially in older adults.

Randomized controlled trials and meta-analyses have shown that vitamin D supplementation, particularly when combined with calcium, reduces the risk of osteoporosis and related fractures. Furthermore, the Endocrine Society, Institute of Medicine, and other major health organizations recommend vitamin D for bone health across the lifespan, from childhood through old age. In summary, the use of vitamin D to support the skeletal system is not only traditional but is also underpinned by a robust body of scientific evidence, making it a mainstay in the prevention and treatment of bone diseases.

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