Relationship: Skeletal System (Bones) and vitamin D3

Evidence supporting the use of: Vitamin D3
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D3 (cholecalciferol) is scientifically validated in its role supporting the skeletal system, particularly bone health. Vitamin D3 is essential for calcium absorption in the intestines, which is critical for maintaining proper bone mineralization and strength. Deficiency in vitamin D3 leads to impaired bone mineralization, resulting in conditions such as rickets in children and osteomalacia or osteoporosis in adults. Multiple randomized controlled trials and meta-analyses have demonstrated that adequate vitamin D3 intake, often in combination with calcium, reduces bone loss and fracture risk, especially in older adults.

Regulatory bodies such as the Institute of Medicine (now the National Academy of Medicine) and the Endocrine Society recognize vitamin D’s central role in bone health, recommending supplementation in cases of deficiency or limited sun exposure. The robust scientific consensus is reflected in clinical guidelines worldwide. Furthermore, vitamin D receptors are present in bone cells (osteoblasts and osteoclasts), and vitamin D3 directly influences bone remodeling processes.

In summary, the use of vitamin D3 to support the skeletal system is supported by high-quality scientific evidence and is a standard medical practice for preventing and treating bone disorders related to vitamin D deficiency.

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Other ingredients that support Skeletal System (Bones)

alfalfa
alpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
Comfrey
Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Eucommia ulmoides
Estrogen
fibroblast growth factor
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein

Other body systems supported by vitamin D3

Blood
Brain
Circulatory System
Glandular System
Heart
Immune System
Intestinal System
Kidneys
Lungs
Mitochondria
Muscles
Parathyroid Glands
Respiratory System
Skeletal System (Bones)
Skin
Small Intestines
Teeth

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Evidence supporting the use of: Vitamin D3
For the body system: Skeletal System (Bones)

Table of Contents

Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by vitamin D3

Products containing vitamin D3

Health Concerns

Brands

Evidence supporting the use of: Vitamin D3For the body system: Skeletal System (Bones)

Table of Contents

Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by vitamin D3

Products containing vitamin D3

Evidence supporting the use of: Vitamin D3
For the body system: Skeletal System (Bones)