Relationship: Skeletal System (Bones) and vitamin K

Evidence supporting the use of: Vitamin K
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin K is scientifically validated as important for bone health. Vitamin K, particularly K2 (menaquinone), is involved in the carboxylation of osteocalcin, a protein that binds calcium in bones and is essential for bone mineralization. Several observational studies and randomized controlled trials have found that adequate vitamin K intake is associated with higher bone mineral density and reduced fracture risk, especially in postmenopausal women. Meta-analyses have concluded that vitamin K supplementation can modestly increase bone mineral density and may reduce fracture incidence, though the effects are more pronounced in populations with low baseline vitamin K status or at higher risk of osteoporosis.

Mechanistically, vitamin K is necessary for the activation of bone matrix proteins and helps regulate calcium deposition, preventing it from accumulating in arteries and instead directing it to bones. The Institute of Medicine and numerous clinical guidelines recognize the role of vitamin K in bone metabolism, though they do not universally recommend supplementation unless deficiency is present. While more research is needed to fine-tune dosing and population benefit, the scientific consensus is that vitamin K is a valid and important nutrient for skeletal health.

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Other ingredients that support Skeletal System (Bones)

alfalfa
alpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
Comfrey
Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Eucommia ulmoides
Estrogen
fibroblast growth factor
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein

Other body systems supported by vitamin K

Arteries
Blood
Capillaries
Circulatory System
Gums
Heart
Skeletal System (Bones)
Structural System
Teeth

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Evidence supporting the use of: Vitamin K
For the body system: Skeletal System (Bones)

Table of Contents

Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by vitamin K

Products containing vitamin K

Health Concerns

Brands

Evidence supporting the use of: Vitamin KFor the body system: Skeletal System (Bones)

Table of Contents

Synopsis

Other ingredients that support Skeletal System (Bones)

Other body systems supported by vitamin K

Products containing vitamin K

Evidence supporting the use of: Vitamin K
For the body system: Skeletal System (Bones)