Evidence supporting the use of: Vitamin K (unspecified)
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin K is scientifically validated as important for skeletal system (bone) health. The primary mechanism involves its role as a cofactor for the enzyme gamma-glutamyl carboxylase, which is essential for the carboxylation of osteocalcin, a protein produced by osteoblasts that binds calcium in the bone matrix. Without adequate vitamin K, osteocalcin remains undercarboxylated and less effective at binding calcium, which can impair bone mineralization. Numerous observational studies have shown that low vitamin K status is associated with lower bone mineral density and increased risk of fractures, particularly in postmenopausal women. Some randomized controlled trials suggest that vitamin K supplementation (especially K2, but also K1) can reduce bone loss and may lower fracture risk, though findings are variable and more robust research is needed. Because of these mechanisms and supporting evidence, vitamin K is recognized in clinical guidelines as a nutrient important for bone health, though it is not typically recommended as a standalone treatment for osteoporosis. Nevertheless, adequate dietary intake of vitamin K is considered essential for optimal skeletal health, supporting its use in this context.

More about Vitamin K (unspecified)
More about Skeletal System (Bones)

Other body systems supported by Vitamin K (unspecified)

Arteries
Blood
Capillaries
Circulatory System
Gums
Skeletal System (Bones)

Products containing Vitamin K (unspecified)

We currently have no products on Vitabase that contain this ingredient.