Evidence supporting the use of: Arbutin
For the health condition: Skin Care (general)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Arbutin is a glycosylated hydroquinone derived from plants such as bearberry, and it is commonly used in skin care for its skin-lightening and depigmenting effects. Scientific research supports its use, primarily for addressing hyperpigmentation conditions like melasma, age spots, and post-inflammatory hyperpigmentation. Arbutin works by inhibiting tyrosinase, an enzyme crucial to melanin synthesis, thereby reducing the formation of melanin in the skin. Several in vitro and clinical studies have demonstrated that topical application of arbutin can effectively lighten hyperpigmented areas with a favorable safety profile compared to other agents like hydroquinone, which can cause skin irritation and potential cytotoxicity.

Alpha-arbutin, a more stable and water-soluble form, is also widely used in cosmetic products and has shown significant efficacy in reducing UV-induced pigmentation in clinical trials. While most studies are short-term and focus on mild-to-moderate hyperpigmentation, the consistent results across different populations and formulations give strong support for its use. No major adverse effects have been reported with typical topical use, although rare cases of irritation have occurred. Overall, the scientific evidence for arbutin's use in general skin care—especially for brightening and evening out skin tone—is robust and growing, warranting a high rating.

More about Arbutin
More about Skin Care (general)

Products containing Arbutin

We currently have no products on Vitabase that contain this ingredient.