Evidence supporting the use of: Carnosine
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Carnosine is a dipeptide composed of beta-alanine and histidine, naturally present in human tissues, including the skin. It has gained attention in dermatology primarily due to its antioxidant and antiglycation properties. Scientific studies have shown that carnosine can protect skin cells from oxidative stress and inhibit the formation of advanced glycation end products (AGEs), which contribute to skin aging, loss of elasticity, and wrinkle formation. For example, in vitro studies demonstrate that carnosine scavenges reactive oxygen species and protects cellular components from glycation-induced damage. Some animal studies and limited human trials indicate that topical application of carnosine-containing formulations may improve skin elasticity and hydration and reduce visible signs of aging.
However, the clinical evidence in humans is still limited, with most data derived from laboratory and animal experiments rather than robust, large-scale human trials. Consequently, while the mechanistic rationale is strong and preliminary data are promising, the overall evidence level is moderate. Carnosine is thus considered scientifically justified for general skin care support, particularly for its potential anti-aging effects, but further high-quality clinical trials are needed to confirm its efficacy and determine optimal usage.
Other ingredients used for Skin Care (general)
Aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
L-cysteine
L-glutathione
L-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
Almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
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Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Flavans
Geraniol
Glycolic acid
Glyceryl oleate
Gac
Glucosylceramide
Glycosylceramides
Haematococcus pluvialis
Heartsease
Himalayan Salt
Houttuynia
Kachnar
Loquat
Lilium polyphyllum
Linseed Oil
Limonene
Leptospermum scoparium
Mesua
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Mung Bean
Manzanita
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Phytofluene
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Phytoene
Panthenol
Pointed gourd
Rockweed
Rose
Snakeroot
Silk protein
Shark oil
Sulfur
silica
Sargassum
Tyrosinase
Triglycerides
Taraxacum
Tropical jewel hisbiscus
vegetable oil
Verbascoside
Witch Hazel
Xanthophyll
Yuzu
Other health conditions supported by Carnosine
Aging (prevention)Alzheimer's Disease
Cardiovascular Disease
Diabetes
Diabetic Retinopathy
Free Radical Damage
Inflammation
Memory and Brain Function
Skin Care (general)
Wrinkles