Evidence supporting the use of: Carnosine
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Carnosine is a dipeptide composed of beta-alanine and histidine, naturally present in human tissues, including the skin. It has gained attention in dermatology primarily due to its antioxidant and antiglycation properties. Scientific studies have shown that carnosine can protect skin cells from oxidative stress and inhibit the formation of advanced glycation end products (AGEs), which contribute to skin aging, loss of elasticity, and wrinkle formation. For example, in vitro studies demonstrate that carnosine scavenges reactive oxygen species and protects cellular components from glycation-induced damage. Some animal studies and limited human trials indicate that topical application of carnosine-containing formulations may improve skin elasticity and hydration and reduce visible signs of aging.

However, the clinical evidence in humans is still limited, with most data derived from laboratory and animal experiments rather than robust, large-scale human trials. Consequently, while the mechanistic rationale is strong and preliminary data are promising, the overall evidence level is moderate. Carnosine is thus considered scientifically justified for general skin care support, particularly for its potential anti-aging effects, but further high-quality clinical trials are needed to confirm its efficacy and determine optimal usage.

More about Carnosine
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Products containing Carnosine

We currently have no products on Vitabase that contain this ingredient.