Evidence supporting the use of: Fatty Acid Esters (Unspecified)
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fatty acid esters are widely used in skin care formulations due to their emollient properties, ability to enhance skin barrier function, and compatibility with various skin types. These compounds are typically derived by esterifying fatty acids (such as those from plant oils) with alcohols (e.g., glycerol, isopropanol), resulting in ingredients like isopropyl myristate, ethylhexyl palmitate, and glyceryl stearate. Scientific studies and dermatological assessments support their use as skin conditioners, moisturizers, and delivery agents for active ingredients. Fatty acid esters are valued for their ability to reduce transepidermal water loss (TEWL), soften the skin, and improve product texture and spreadability. They are generally non-irritating and well-tolerated by most skin types, although some (like isopropyl myristate) may contribute to comedogenicity in acne-prone individuals.

While most research focuses on the safety, tolerability, and functional properties of fatty acid esters rather than direct therapeutic effects, their role in maintaining skin hydration and integrity is well documented in cosmetic science literature. There is moderate scientific validation (rated 3/5) for their use in general skin care, primarily as supportive agents rather than active treatments for dermatological conditions.

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