Evidence supporting the use of: Gac
For the health condition: Skin Care (general)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Gac (Momordica cochinchinensis), a fruit native to Southeast Asia, has a long history of traditional use in skin care, primarily in Vietnam and neighboring countries. Traditionally, Gac is consumed for its perceived health benefits, with its bright red aril being particularly valued for its richness in carotenoids—especially beta-carotene and lycopene—which are known antioxidants. In folklore, Gac oil has been applied topically or consumed to promote healthy, glowing skin and to address general skin concerns, likely due to its reputation for supporting overall vitality and protection from oxidative damage.
While traditional use is well-documented, scientific validation remains limited. A handful of laboratory and animal studies suggest that the carotenoids and vitamin E present in Gac have antioxidant properties that could theoretically benefit skin health by reducing oxidative stress and supporting skin barrier function. However, there is a lack of robust clinical trials in humans specifically evaluating Gac’s efficacy in treating or supporting general skin care. Most evidence is extrapolated from the known benefits of carotenoids and antioxidants in skin health rather than direct studies on Gac itself. Thus, while traditional use is notable and biologically plausible mechanisms exist, high-quality scientific evidence supporting Gac for skin care is currently modest.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
Other health conditions supported by Gac
Aging (prevention)Cancer (natural therapy for)
Cancer (prevention)
Free Radical Damage
Inflammation
Skin Care (general)
Ulcers