Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glucosylceramide is a type of glycosphingolipid found in the outermost layer of the skin (stratum corneum) and is important for maintaining the skin’s barrier function and hydration. Scientific studies, especially from Japan and other East Asian countries, have investigated both topical and oral supplementation of plant-derived glucosylceramides for skin health. Several randomized, placebo-controlled trials have demonstrated that oral glucosylceramide extracted from plants like rice or konjac can improve skin hydration, reduce transepidermal water loss (TEWL), and help relieve symptoms of dry skin in healthy adults and individuals with mild eczema. The mechanism is believed to involve the upregulation of natural ceramide production and enhanced skin barrier repair.

Topically, glucosylceramide is included in some moisturizers and skincare formulations to support and replenish the skin’s lipid barrier. Scientific evidence for topical efficacy is less robust than for oral supplementation, but some in vitro and clinical studies support its moisturizing and barrier-strengthening properties.

However, while the evidence is promising, most studies are small and short-term, and there is heterogeneity in populations, dosages, and formulations. The ingredient is not a primary treatment for skin diseases but may be a supportive measure for general skin hydration and barrier function. Overall, the use of glucosylceramide for skin care is supported by scientific evidence, but larger and longer-term studies are needed to fully validate its effectiveness.

More about Glucosylceramide
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Other ingredients used for Skin Care (general)

3,3'-dihydroxy-B-carotene-4,4'-dione
Abalone
Algal protein
Allantoin
Almond fruit
Aloe vera
Alpha hydroxy acids
alpha-terpineol
amaranth
Anserina
anthocyanidins
anthocyanins
apple
apricot
arbutin
argan nut oil
Asam gelugor
Ascophyllum nodosum
astaxanthin
avocado
azelaic acid
beet
behenic acid
beta-carotene
beta-zeacarotene
Biopeptide
birch
bird\'s nest
bisabolene
black currant
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borage
bottle gourd
Brassica
butternut
California chia
camphor oil
candelilla wax
Carnosine
castile soap
catalase
cereal grass
chervil
chickweed
citral
cocoa butter
colostrum
copaiba oil
cryptoxanthin
cucumber
currant
d-alpha tocopherol
David\'s milkberry
dog rose
dulse
dulse leaf
Dunaliella salina
egg
emu oil
flavans
Gac
geraniol
Glucosylceramide
glyceryl oleate
Glycolic acid
Glycosylceramides
goji berry
Haematococcus pluvialis
Heartsease
heartwood
Himalayan salt
Houttuynia
hyaluronic acid
Kachnar
keratin
L-cysteine
L-glutathione
L-histidine
Leptospermum scoparium
Lilium polyphyllum
limonene
linoleic acid (LA)
linseed oil
loquat
lovage
lychee
magnesium
mandarin
mango
manzanita
Mesua
mixed carotenoids
Mung bean
Nectarine
Night jessamine
Oak
oat
omega-3 fatty acids
orchid
oryza
palmitic acid
Panthenol
Pelvetia canaliculata
Phlebodium decumanum
Phytoene
Phytofluene
procyanidin
procyanidol
pumpkin
radish
red clover
rockweed
root tuber
rose
Sargassum
sarsaparilla
sea salt
sesame
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silica
silicon
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spinach
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Tyrosinase
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vegetable oil
Verbascoside
vitamin A
vitamin C
vitamin E
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Other health conditions supported by Glucosylceramide

Inflammation
Psoriasis
Skin Care (general)

Products containing Glucosylceramide

We currently have no products on Vitabase that contain this ingredient.