Evidence supporting the use of: Glycosylceramides
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Glycosylceramides are a class of lipid molecules found naturally in plant and animal cell membranes and have gained attention in dermatology and skin care primarily due to their role in the structure and function of the skin barrier. Scientific studies have demonstrated that glycosylceramides, particularly those derived from plants such as wheat and konjac, can help improve skin hydration and barrier function when taken orally or applied topically. The mechanism is believed to involve the enhancement of stratum corneum ceramide content, which reduces transepidermal water loss and supports skin integrity.
Clinical trials have shown that oral supplementation with plant-derived glycosylceramides can lead to measurable improvements in skin moisture and elasticity in healthy adults and individuals with dry skin conditions. For example, a 2018 randomized, double-blind, placebo-controlled study found that oral wheat extract oil rich in glycosylceramides significantly improved skin hydration and reduced roughness compared to placebo. Other in vitro and animal studies also support the role of glycosylceramides in maintaining skin barrier function.
While more high-quality, large-scale human studies are needed to establish definitive efficacy and optimal dosing, the current scientific evidence suggests a beneficial role of glycosylceramides in supporting general skin health, particularly by enhancing hydration and barrier properties.
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alpha-terpineol
amaranth
Anserina
anthocyanidins
anthocyanins
apple
apricot
arbutin
argan nut oil
Asam gelugor
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astaxanthin
avocado
azelaic acid
beet
behenic acid
beta-carotene
beta-zeacarotene
Biopeptide
birch
bird\'s nest
bisabolene
black currant
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borage
bottle gourd
Brassica
butternut
California chia
camphor oil
candelilla wax
Carnosine
castile soap
catalase
cereal grass
chervil
chickweed
citral
cocoa butter
colostrum
copaiba oil
cryptoxanthin
cucumber
currant
d-alpha tocopherol
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dog rose
dulse
dulse leaf
Dunaliella salina
egg
emu oil
flavans
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glyceryl oleate
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goji berry
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hyaluronic acid
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L-cysteine
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limonene
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linseed oil
loquat
lovage
lychee
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mango
manzanita
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orchid
oryza
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rockweed
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vitamin C
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