Evidence supporting the use of: Panthenol
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Panthenol, also known as provitamin B5, is widely used in skin care due to its well-documented moisturizing, soothing, and barrier-supporting properties. Several clinical and preclinical studies have demonstrated its efficacy in improving skin hydration, reducing transepidermal water loss, and enhancing skin barrier function. Panthenol is readily absorbed by the skin and converted to pantothenic acid, a component essential for the synthesis of coenzyme A, which is involved in lipid metabolism and skin regeneration.

Research has shown that topical application of panthenol can accelerate wound healing, reduce inflammation, and alleviate symptoms of irritation, making it valuable not only for general skin care but also for the management of minor skin injuries, dermatitis, and other conditions characterized by compromised skin barrier. In addition, panthenol has been found to improve skin softness and elasticity, likely due to its humectant properties, which help retain moisture within the stratum corneum.

Multiple peer-reviewed studies and dermatological reviews—such as those found in the Journal of Dermatological Treatment and Skin Pharmacology and Physiology—support these claims, providing a solid scientific basis for panthenol’s inclusion in a wide array of skin care products, from moisturizers and serums to after-sun lotions. Overall, the use of panthenol in general skin care is strongly validated by scientific evidence.

More about Panthenol
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Products containing Panthenol

We currently have no products on Vitabase that contain this ingredient.