Evidence supporting the use of: Phospholipids (unspecified)
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phospholipids are increasingly incorporated into skin care formulations based on scientific evidence supporting their beneficial effects on the skin barrier, hydration, and delivery of active ingredients. Phospholipids, such as phosphatidylcholine, are key structural components of cell membranes and are naturally present in the skin's stratum corneum. Studies have shown that topical application of phospholipids can enhance skin hydration by improving the lipid matrix and reducing transepidermal water loss (TEWL). Additionally, phospholipids act as natural emulsifiers and can increase the penetration and stability of other active ingredients in cosmetic formulations.

Research demonstrates that phospholipids possess emollient and skin-soothing properties, and their biocompatibility makes them well-tolerated even by sensitive skin types. Their ability to form liposomes or vesicles has been leveraged in dermatology to deliver drugs and bioactives more effectively to deeper skin layers. While direct clinical studies on phospholipids alone for skin care are somewhat limited, the mechanistic rationale and supportive in vitro and in vivo data provide moderate scientific support for their inclusion in skin care products. Thus, the use of phospholipids in skin care is justified by scientific evidence, particularly for their roles in moisturizing, barrier repair, and delivery enhancement.

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