Evidence supporting the use of: Phytofluene
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Phytofluene is a colorless carotenoid found in certain fruits and vegetables, and it is also present in tomato-based extracts that are sometimes used in oral and topical skin care formulations. The scientific interest in phytofluene for skin care primarily centers around its antioxidant properties and its ability to absorb ultraviolet (UV) light, particularly in the UVB and UVA range. Several in vitro (test tube) and animal studies suggest that phytofluene, often in combination with other carotenoids like phytoene and lycopene, can help protect skin cells from UV-induced oxidative stress and inflammation. There is also some evidence from human studies that oral supplementation with tomato-based extracts containing phytofluene may provide mild photoprotective effects, as measured by reduced erythema (skin redness) following UV exposure.

However, the evidence base is still limited. Most clinical studies have tested whole tomato extracts or mixtures of carotenoids rather than isolated phytofluene, making it difficult to attribute effects specifically to this compound. There is a lack of large-scale, well-controlled clinical trials directly measuring the impact of phytofluene on skin aging, pigmentation, or other specific skin concerns. Therefore, while its use in skin care has some scientific rationale, the evidence supporting its effectiveness is considered preliminary and not yet robust.

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Products containing Phytofluene

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